juxtacortical osteosarcoma - ترجمة إلى العربية
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juxtacortical osteosarcoma - ترجمة إلى العربية

MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
C-fos; Oncogene proteins v-fos; V-fos FBJ murine osteosarcoma viral oncogene homolog; CFos; FOS (gene); C-Fos
  • Mixed neural cultures derived from rat embryos were grown under normal conditions (left) or treated with 55mM Potassium for 5 hours (right). Cultures were then stained with antibody to the [[intermediate filament]] protein [[vimentin]] (green), antibody to cFos (red) and with a DNA binding dye (blue). The vimentin antibody reveals non-neuronal cells and the DNA dye shows the nuclei of all cells. The potassium treatment depolarizes the neurons and induces strong expression of cFos in neuronal cell bodies as shown in the right image. Cell culture, Image and antibody generation all performed in the [[EnCor Biotechnology]] laboratory.

juxtacortical osteosarcoma      
‎ ساركومةٌ عَظْمِيَّةٌ مُجَاوِرَةٌ للقِشْرَة‎
osteogenic sarcoma         
  • [[X-ray]] of osteosarcoma of the distal femur in a dog
  • Histopathology of osteosarcoma, showing tumor cells with high [[nuclear pleomorphism]], but relatively less so in cells entrapped in neoplastic bone matrix (appearing pink on this [[H&E stain]]ed slide).
  • High-magnification micrograph showing osteoid formation in an osteosarcoma [[H&E stain]]
  • Predilections of osteosarcoma
BONE CANCER THAT IS LOCATED IN BONE THAT HAS MATERIAL BASIS IN CELLS OF MESENCHYMAL ORIGIN
Osteosarcomas; Osteogenic sarcoma
‎ ساركومةٌ عَظْمِيَّةُ المَنْشَأ, ساركومةٌ عَظْمِيَّةٌ‎
osteosarcoma         
  • [[X-ray]] of osteosarcoma of the distal femur in a dog
  • Histopathology of osteosarcoma, showing tumor cells with high [[nuclear pleomorphism]], but relatively less so in cells entrapped in neoplastic bone matrix (appearing pink on this [[H&E stain]]ed slide).
  • High-magnification micrograph showing osteoid formation in an osteosarcoma [[H&E stain]]
  • Predilections of osteosarcoma
BONE CANCER THAT IS LOCATED IN BONE THAT HAS MATERIAL BASIS IN CELLS OF MESENCHYMAL ORIGIN
Osteosarcomas; Osteogenic sarcoma
ساركومةٌ عَظْمِيَّة

تعريف

Osteosarcoma
·noun A tumor having the structure of a sacroma in which there is a deposit of bone; sarcoma connected with bone.

ويكيبيديا

Protein c-Fos

Protein c-Fos is a proto-oncogene that is the human homolog of the retroviral oncogene v-fos. It is encoded in humans by the FOS gene. It was first discovered in rat fibroblasts as the transforming gene of the FBJ MSV (Finkel–Biskis–Jinkins murine osteogenic sarcoma virus) (Curran and Tech, 1982). It is a part of a bigger Fos family of transcription factors which includes c-Fos, FosB, Fra-1 and Fra-2. It has been mapped to chromosome region 14q21→q31. c-Fos encodes a 62 kDa protein, which forms heterodimer with c-jun (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1) complex which binds DNA at AP-1 specific sites at the promoter and enhancer regions of target genes and converts extracellular signals into changes of gene expression. It plays an important role in many cellular functions and has been found to be overexpressed in a variety of cancers.